Cancer Stem Cell Markers Antibody Sampler Pack

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SKU:
ABSP018
Product Type:
Antibody
Size:
Antibody Sampler Pack
Size:
8 X 20μL
Reactivity:
Human
Mouse
Rat
Monkey
Analytes:
CD44
CD133/PROM1
ALDH1A1
Sox2
Oct4
Nanog
CD24
EpCAM
  • Anti-CD44 Antibody -Knockout Validated (CAB12410)
  • Anti-CD133 Antibody -Knockout Validated (CAB12711)
  • Anti-ALDH1A1 [ARC52440] Monoclonal Antibody (CAB0157)
  • Anti-SOX2 Monoclonal Antibody -Knockout Validated (CAB19118)
  • Anti-OCT4 Antibody (CAB7920)
  • Anti-Nanog [ARC58438] Monoclonal Antibody (CAB22625)
  • Anti-mouse CD24 Polyclonal Antibody (CAB24878)
  • Anti-EpCAM [ARC0521] Monoclonal Antibody (CAB1107)

Description

Cancer Stem Cell Markers Antibody Sampler Pack

The Cancer Stem Cell Markers Antibody Sampler Pack from Assay Genie brings together 8 rigorously validated antibodies spanning the key nodes of this pathway, supplied in a convenient 20µL trial size. It lets researchers screen an entire signalling axis in a single, cost-effective pack — validated for applications including ELISA, IF, IF/ICC, IHC, IHC-P, IP, WB — before committing to full-size vials. Each antibody is also available individually in a full 100µL size.

TargetAntibodyCat. No.HostReactivityApplicationsSize
CD44Anti-CD44 Antibody -Knockout ValidatedCAB12410-20RabbitHuman, MouseWBIHC-PIF/ICCELISA20µL
CD133/PROM1Anti-CD133 Antibody -Knockout ValidatedCAB12711-20RabbitHuman, Mouse, RatWBIF/ICCIPELISA20µL
ALDH1A1Anti-ALDH1A1 [ARC52440] Monoclonal AntibodyCAB0157-20RabbitHuman, Mouse, RatWBIF/ICCIPELISA20µL
Sox2Anti-SOX2 Monoclonal Antibody -Knockout ValidatedCAB19118-20RabbitMouse, RatWBIF/ICCELISA20µL
Oct4Anti-OCT4 AntibodyCAB7920-20RabbitHuman, MouseWBIHC-PELISA20µL
NanogAnti-Nanog [ARC58438] Monoclonal AntibodyCAB22625-20RabbitHuman, Mouse, RatWBELISA20µL
CD24Anti-mouse CD24 Polyclonal AntibodyCAB24878-20RabbitHuman, Mouse, Rat, MonkeyWBIHCIF20µL
EpCAMAnti-EpCAM [ARC0521] Monoclonal AntibodyCAB1107-20RabbitHuman, Mouse, RatWBIHC-PELISA20µL

Cancer stem cells are a subpopulation of tumor cells defined by their capacity for self-renewal, multilineage differentiation, and tumor initiation, and they are implicated in metastasis, dormancy, and resistance to conventional therapy. These cells are identified and isolated using combinations of surface and intracellular markers, several of which also contribute functionally to the stem-like phenotype. The hyaluronan receptor CD44 mediates adhesion, migration, and signaling and is a widely used cancer stem-cell marker, frequently employed in combination with low expression of CD24 to enrich tumor-initiating populations in breast and other carcinomas. The pentaspan membrane glycoprotein CD133/PROM1 marks stem-like cells in numerous tumors, while the epithelial cell adhesion molecule EpCAM identifies tumor-initiating and circulating tumor cells. The detoxifying enzyme ALDH1A1 confers high aldehyde dehydrogenase activity that is both a functional assay readout and a contributor to chemoresistance. Underlying the stem-like state is a core transcriptional network of pluripotency factors, comprising Sox2, Oct4, and Nanog, which cooperate to sustain self-renewal, suppress differentiation, and reprogram tumor cells toward a stem-like identity; their reactivation in tumors correlates with aggressiveness and poor prognosis. Because cancer stem cells survive treatments that eliminate the bulk tumor, they are considered a key source of minimal residual disease and relapse, motivating therapeutic strategies aimed at their elimination or forced differentiation. Accurate identification of these cells requires marker panels rather than single antigens, given heterogeneity across and within tumor types. Profiling surface markers together with the pluripotency transcription factors and ALDH1A1 enables robust characterization of stem-like subpopulations. This pack brings together validated antibodies against CD44, CD133/PROM1, ALDH1A1, Sox2, Oct4, Nanog, CD24, and EpCAM for studying cancer stem cells.

AnalyteAlternate Names
CD44Hyaluronate receptor, Phagocytic glycoprotein 1, HCAM, Pgp1
CD133/PROM1PROM1, Prominin-1, CD133, AC133
ALDH1A1ALDH1, Aldehyde dehydrogenase 1A1, RALDH1
Sox2SRY-box transcription factor 2, SOX-2
Oct4POU5F1, OCT4, OCT3, Octamer-binding transcription factor 3/4, OTF3
NanogNANOG, Nanog homeobox, Homeobox transcription factor Nanog
CD24Signal transducer CD24, Heat stable antigen, HSA
EpCAMEpithelial cell adhesion molecule, TACSTD1, CD326, TROP1, GA733-2
SpecificationDetail
Pack Format8 antibodies, 20µL each (trial size)
StorageStore at -20°C upon receipt
Shelf Life12 months from date of receipt
ShippingGel pack
Scale-upEvery antibody is also available individually in a full 100µL size

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