Synaptic Markers Antibody Sampler Pack

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SKU:
ABSP034
Product Type:
Antibody
Size:
Antibody Sampler Pack
Size:
8 X 20μL
Reactivity:
Human
Mouse
Rat
Analytes:
Synaptophysin
PSD-95
Synapsin-1
SNAP25
Synaptotagmin
VGLUT1
Gephyrin
Homer1
  • Anti-Synaptophysin Antibody (CAB6344)
  • Anti-PSD95 Antibody (CAB6194)
  • Anti-Synapsin II [ARC2166] Monoclonal Antibody (CAB19542)
  • Anti-SNAP25 [ARC0736] Monoclonal Antibody (CAB2234)
  • Anti-Synaptotagmin XI (SYT11) [ARC59135] Monoclonal Antibody (CAB23089)
  • Anti-SLC17A7 Antibody (CAB12879)
  • Anti-Gephyrin [ARC1109] Monoclonal Antibody (CAB4729)
  • Anti-Homer1 [ARC3008] Monoclonal Antibody (CAB21136)

Description

Synaptic Markers Antibody Sampler Pack

The Synaptic Markers Antibody Sampler Pack from Assay Genie brings together 8 rigorously validated antibodies spanning the key nodes of this pathway, supplied in a convenient 20µL trial size. It lets researchers screen an entire signalling axis in a single, cost-effective pack — validated for applications including ELISA, IF/ICC, IHC-P, IP, WB — before committing to full-size vials. Each antibody is also available individually in a full 100µL size.

TargetAntibodyCat. No.HostReactivityApplicationsSize
SynaptophysinAnti-Synaptophysin AntibodyCAB6344-20RabbitHuman, Mouse, RatWBIHC-PIF/ICCIPELISA20µL
PSD-95Anti-PSD95 AntibodyCAB6194-20RabbitHuman, Mouse, RatWBIF/ICCELISA20µL
Synapsin-1Anti-Synapsin II [ARC2166] Monoclonal AntibodyCAB19542-20RabbitHuman, Mouse, RatWBIF/ICCELISA20µL
SNAP25Anti-SNAP25 [ARC0736] Monoclonal AntibodyCAB2234-20RabbitMouse, RatWBELISA20µL
SynaptotagminAnti-Synaptotagmin XI (SYT11) [ARC59135] Monoclonal AntibodyCAB23089-20RabbitHuman, Mouse, RatWBELISA20µL
VGLUT1Anti-SLC17A7 AntibodyCAB12879-20RabbitHuman, MouseWBIF/ICCELISA20µL
GephyrinAnti-Gephyrin [ARC1109] Monoclonal AntibodyCAB4729-20RabbitHuman, Mouse, RatWBELISA20µL
Homer1Anti-Homer1 [ARC3008] Monoclonal AntibodyCAB21136-20RabbitHuman, RatWBELISA20µL

The synapse is the fundamental unit of neuronal communication, and its molecular architecture is organized into distinct presynaptic and postsynaptic compartments whose components can be detected as markers of synapse number, identity, and integrity. On the presynaptic side, neurotransmitter release depends on a coordinated machinery of vesicle proteins. Synaptophysin is an abundant integral membrane glycoprotein of synaptic vesicles widely used as a general marker of presynaptic terminals and synaptic density. Synapsin-1 tethers vesicles to the actin cytoskeleton and regulates their mobilization into the readily releasable pool, while Synaptotagmin functions as the calcium sensor that triggers fast, synchronous vesicle fusion. The fusion event itself is mediated by SNARE proteins, including SNAP25, which assembles with syntaxin and VAMP to drive membrane merger during exocytosis. Excitatory glutamatergic terminals are specifically identified by VGLUT1, the vesicular glutamate transporter that loads glutamate into synaptic vesicles. Across the cleft, the postsynaptic density organizes receptor clustering and downstream signaling. PSD-95 is the principal scaffolding protein of excitatory postsynaptic densities, anchoring glutamate receptors and linking them to signaling complexes, and Homer1 further scaffolds metabotropic glutamate receptors and couples them to intracellular calcium stores. Inhibitory synapses are defined by a distinct scaffold, Gephyrin, which clusters glycine and GABA-A receptors at the postsynaptic membrane. Together these proteins allow the discrimination of excitatory versus inhibitory contacts and the quantification of synaptic loss, a feature common to neurodegenerative, neurodevelopmental, and psychiatric disorders where synapse dysfunction often precedes neuronal death. This pack brings together validated antibodies against Synaptophysin, PSD-95, Synapsin-1, SNAP25, Synaptotagmin, VGLUT1, Gephyrin, and Homer1 to support comprehensive analysis of synaptic structure and function.

AnalyteAlternate Names
SynaptophysinSYP, Synaptophysin, Major synaptic vesicle protein p38, MRX96
PSD-95DLG4, PSD-95, Postsynaptic density protein 95, SAP90
Synapsin-1SYN1, Synapsin-1, SYN1a, SYNI
SNAP25Synaptosomal-associated protein 25, SNAP-25, SEC9
SynaptotagminSYT1, Synaptotagmin-1, P65, SVP65
VGLUT1SLC17A7, VGLUT1, Vesicular glutamate transporter 1, BNPI
GephyrinGPHN, Gephyrin, GPH
Homer1HOMER1, Homer protein homolog 1, Vesl-1
SpecificationDetail
Pack Format8 antibodies, 20µL each (trial size)
StorageStore at -20°C upon receipt
Shelf Life12 months from date of receipt
ShippingGel pack
Scale-upEvery antibody is also available individually in a full 100µL size

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