The FKBP11 Polyclonal Antibody (CAB23048) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.FKBP11, also known as FK506-binding protein 11, is a member of the FK506-binding protein family and is involved in regulating the activity of proteins through its chaperone function. Research on FKBP11 has shown its role in various cellular processes, including protein trafficking, proteasomal degradation, and signaling pathways.By using the FKBP11 Polyclonal Antibody, researchers can detect and analyze FKBP11 protein expression in different cell types, making it an ideal tool for studies in molecular biology, cell biology, and drug discovery.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
FKBP11 Polyclonal Antibody
SKU:
CAB23048
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
FKBP19, FKBP11
Positive Sample:
RPMI 8226, Mouse pancreas, Rat pancreas
Calculated MW:
98kDa
Observed MW:
22kDa
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).
Purification Method
Affinity purification
Gene ID
51303
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using FKBP11 Rabbit pAb (CAB23048) at 1:600 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
