ARHGEF7 Rabbit Polyclonal Antibody (CAB1108)

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SKU:
CAB1108
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience
Reactivity:
Human, Mouse
Synonyms:
P50, P85, PAK3, PIXB, COOL1, P50BP, COOL-1, P85SPR, BETA-PIX, P85COOL1, Nbla10314, ARHGEF7
Research Use:
Neuroscience

Description

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ARHGEF7 Antibody (CAB1108)

The ARHGEF7 Antibody (CAB1108) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity towards human samples and is validated for use in Western blot applications. By binding specifically to the ARHGEF7 protein, researchers can effectively detect and analyze its expression in a variety of cell types, making it ideal for studies in cell biology and signal transduction mechanisms.ARHGEF7 plays a crucial role in regulating cytoskeletal dynamics and cell migration, making it a key player in processes like cell division and cell motility.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:ARHGEF7 Antibody
SKU:CAB1108
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MNSA EQTV TWLI TLGV LESP KKTI SDPE GFLQ ASLK DGVV LCRL LERL LPGT IEKT FDAN DLYQ GQNF NKVL SSLV TLNK VTAD IGLG SDSV CARP SSHR IKSF DSLG SQSL HTRT SKLF QGQY RSLD MTDN SNNQ LVVR AKFN FQQT NEDE LSFS KGDV IHVT RVEE GGWW EGTL NGRT GWFP SNYV REVK ASEK PVSP KSGT LKSP PKGF DTTA INKS YYNV VLQN ILET ENEY SKEL QTVL STYL RPLQ TSEK LSSA
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:P50, P85, PAK3, PIXB, COOL1, P50BP, COOL-1, P85SPR, BETA-PIX, P85COOL1, Nbla10314, ARHGEF7
Positive Sample:SW620, Jurkat, COS-1, COS-7, MCF7, K-562, Mouse lung, Mouse heart
Cellular Localization:Cell Junction, Cell Projection, Cytoplasm, Cell Cortex, Focal Adhesion, Lamellipodium, Ruffle.
Calculated MW:90kDa
Observed MW:86kDa

This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Purification MethodAffinity purification
Gene ID8874
RRIDAB_2758395
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using ARHGEF7 Rabbit pAb (CAB1108) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.

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