The ZEB1 Monoclonal Antibody (CAB21794) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through hybridoma technology, is highly specific to human ZEB1 and has been validated for use in immunofluorescence and immunohistochemistry applications.ZEB1 is known to play a critical role in cancer progression by promoting tumor cell invasion and metastasis through the induction of EMT. Its aberrant expression has been linked to poor prognosis in various cancer types, making it an attractive target for therapeutic intervention.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
ZEB1 Monoclonal Antibody
SKU:
CAB21794
Size:
20μL, 100μL
Reactivity:
Human, Rat
Clone Number:
ARC53599
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method
Affinity purification
Gene ID
6935
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZEB1 Rabbit mAb (CAB21794) at 1:1000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 45s.
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