The TRPS1 Antibody (CAB7743) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, boasts high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TRPS1 protein, this antibody allows for the detection and analysis of TRPS1 expression in various cell types.TRPS1 is known for its involvement in skeletal patterning and maintenance, making it a key player in conditions like trichorhinophalangeal syndrome.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
TRPS1 Antibody
SKU:
CAB7743
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GC79, LGCR, TRPS1
Positive Sample:
Mouse liver, Mouse kidney, Rat brain
Cellular Localization:
Nucleus.
Calculated MW:
142kDa
Observed MW:
160kDa
This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.
Purification Method
Affinity purification
Gene ID
7227
RRID
AB_2772733
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using TRPS1 Rabbit pAb (CAB7743) at 1:10000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
