Mouse Cyclophilin B Recombinant Protein (RPPB1537)

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SKU:
RPPB1537
Product type:
Recombinant Protein
Size:
10ug
Species:
Mouse
Target:
Cyclophilin B
Synonyms:
Peptidyl-prolyl cis-trans isomerase B
Synonyms:
PPIase B
Synonyms:
CYP-S1
Synonyms:
Cyclophilin B
Source:
Escherichia Coli
Uniprot:
P24369
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Description

Product Name:Mouse Cyclophilin B Recombinant Protein
Product Code:RPPB1537
Size:10µg
Species:Mouse
Target:Cyclophilin B
Synonyms:Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:Cyclophilin B protein solution (1mg/ml) containing Phosphate Buffered Saline (pH7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMNDKKKG PKVTVKVYFD LQIGDESVGR VVFGLFGKTV PKTVDNFVAL ATGEKGFGYK NSKFHRVIKD FMIQGGDFTR GDGTGGKSIY GERFPDENFK LKHYGPGWVS MANAGKDTNG SQFFITTVKT SWLDGKHVVF GKVLEGMDVV RKVESTKTDSRDKPLKDVII VDSGKIEVEK PFAIAKE
Biological Activity:Specific activity is > 1,000 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37C in Tris–HCl pH 8.0 using chymotrypsin.

Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.

Cyclophilin B Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (34-216 a.a) and having a molecular mass of 22.7kDa.Cyclophilin B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
UniProt Code:P24369
NCBI GenInfo Identifier:215273926
NCBI Gene ID:19035
NCBI Accession:P24369.2
UniProt Related Accession:P24369
Molecular Weight:23,713 Da
NCBI Full Name:Peptidyl-prolyl cis-trans isomerase B
NCBI Synonym Full Names:peptidylprolyl isomerase B
NCBI Official Symbol:Ppib  
NCBI Official Synonym Symbols:Cphn2; Cphn-2; CyP-20b; AA408962; AA553318; AI844835  
NCBI Protein Information:peptidyl-prolyl cis-trans isomerase B
UniProt Protein Name:Peptidyl-prolyl cis-trans isomerase B
UniProt Synonym Protein Names:CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP
Protein Family:Probable peptidyl-prolyl cis-trans isomerase
UniProt Gene Name:Ppib  
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