The IFNL3 Antibody (CAB5648) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high specificity and reactivity with human samples, making it an ideal choice for researchers working in immunology and virology.Interferon Lambda-3, also known as IFNL3, is a key player in the antiviral immune response, particularly in the case of hepatitis C virus infections. By targeting the IFNL3 protein, this antibody allows for the detection and analysis of Interferon Lambda-3 in various cell types, providing valuable insights into its role in viral defense mechanisms.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
IFNL3 Antibody
SKU:
CAB5648
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recombinant Human IFNL3 Protein, K-562, Mouse thymus
Cellular Localization:
Secreted.
Calculated MW:
22kDa
Observed MW:
24kDa
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Purification Method
Affinity purification
Gene ID
282617
RRID
AB_2766408
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse thymus, using IFNL3 Rabbit pAb (CAB5648) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
