Human AZGP1 Recombinant Protein (RPPB2833)

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SKU:
RPPB2833
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
AZGP1
Synonyms:
Alpha-2-Glycoprotein 1
Synonyms:
Zinc-Binding
Synonyms:
Zinc-Alpha-2-Glycoprotein
Synonyms:
Zn-Alpha-2-Glycoprotein
Source:
Sf9 Insect cells
Uniprot:
P25311
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Description

Product Name:Human AZGP1 Recombinant Protein
Product Code:RPPB2833
Size:10µg
Species:Human
Target:AZGP1
Synonyms:Alpha-2-Glycoprotein 1, Zinc-Binding, Zinc-Alpha-2-Glycoprotein, Zn-Alpha-2-Glycoprotein, Zn-Alpha-2-GP, ZAG, Testicular Tissue Protein Li 227, Alpha-2-Glycoprotein 1, Zinc, Alpha-2-Glycoprotein, Zinc, Zn-Alpha2-Glycoprotein, ZNGP1, ZA2G.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The AZGP1 solution (0.5mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET LKDIVEYYND SNGSHVLQGR FGCEIENNRS SGAFWKYYYD GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA YLEEECPATL RKYLKYSKNI LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT RAGEVQEPEL RGDVLHNGNG TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEASLE HHHHHH

Alpha-2-Glycoprotein 1 Zinc-Binding or AZGP1 is a protein, part of the MHC class 1 protein family. AZGP1 is thought to connect to prolactin-inducible protein (PIP), and not to , B 2-microglobulin (MHC light chain). AZGP1 is secreted from epithelia and can be found in nearly all fluids of the body. In adipocytes, AZGP1 triggers lipid degradation, that leads to a broad fat lost that can be linked to progressive type of cancers.

AZGP1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 283 amino acids (21-298 a.a) and having a molecular mass of 33.2kDa. AZGP1 is fused to a 5 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:AZGP1: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids. Belongs to the MHC class I family.
UniProt Protein Details:

Protein type:Cell adhesion; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: extracellular space; extracellular region; plasma membrane; nucleus; MHC class I protein complex

Molecular Function:peptide antigen binding; protein transmembrane transporter activity; glycoprotein binding; antigen binding; ribonuclease activity

Biological Process: retinal homeostasis; antigen processing and presentation; negative regulation of cell proliferation; antigen processing and presentation of peptide antigen via MHC class I; positive regulation of T cell mediated cytotoxicity; immune response; detection of chemical stimulus involved in sensory perception of bitter taste; cell adhesion

UniProt Code:P25311
NCBI GenInfo Identifier:292495049
NCBI Gene ID:563
NCBI Accession:P25311.2
UniProt Secondary Accession:P25311,O60386, Q5XKQ4, Q8N4N0, D6W5T8,
UniProt Related Accession:P25311
Molecular Weight:
NCBI Full Name:Zinc-alpha-2-glycoprotein
NCBI Synonym Full Names:alpha-2-glycoprotein 1, zinc-binding
NCBI Official Symbol:AZGP1  
NCBI Official Synonym Symbols:ZAG; ZA2G  
NCBI Protein Information:zinc-alpha-2-glycoprotein; zn-alpha-2-GP; Zn-alpha2-glycoprotein; zn-alpha-2-glycoprotein; Alpha-2-glycoprotein, zinc
UniProt Protein Name:Zinc-alpha-2-glycoprotein
Protein Family:Zinc-alpha-2-glycoprotein
UniProt Gene Name:AZGP1  
UniProt Entry Name:ZA2G_HUMAN
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