Human ADAT1 Recombinant Protein (RPPB5789)

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SKU:
RPPB5789
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
ADAT1
Synonyms:
tRNA-specific adenosine deaminase 1
Synonyms:
hADAT1
Synonyms:
tRNA-specific adenosine- 37 deaminase
Synonyms:
ADAT1
Source:
Escherichia Coli
Uniprot:
Q9BUB4
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Description

Product Name:Human ADAT1 Recombinant Protein
Product Code:RPPB5789
Size:10µg
Species:Human
Target:ADAT1
Synonyms:tRNA-specific adenosine deaminase 1, hADAT1, tRNA-specific adenosine- 37 deaminase, ADAT1, ADAT-1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:Adenosine Deaminase tRNA-Specific-1 at 0.1mg/ml, 10mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.

This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.

Adenosine Deaminase tRNA-Specific 1 Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing amino acids 1-502 and having a total molecular mass of 57.7 kda. ADAT-1 contains T7 tag at N-terminus. ADAT1 is purified by proprietary chromatographic techniques.

UniProt Protein Function:ADAT1: Specifically deaminates adenosine-37 to inosine in tRNA- Ala. Belongs to the ADAT1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA processing; EC 3.5.4.34; HydrolaseChromosomal Location of Human Ortholog: 16q23.1Molecular Function: RNA binding; tRNA-specific adenosine deaminase activityBiological Process: tRNA processing
UniProt Protein Details:
NCBI Summary:This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
UniProt Code:Q9BUB4
NCBI GenInfo Identifier:74733201
NCBI Gene ID:23536
NCBI Accession:Q9BUB4.1
UniProt Secondary Accession:Q9BUB4,Q9NVB7, Q9UNG3
UniProt Related Accession:Q9BUB4
Molecular Weight:38,706 Da
NCBI Full Name:tRNA-specific adenosine deaminase 1
NCBI Synonym Full Names:adenosine deaminase, tRNA specific 1
NCBI Official Symbol:ADAT1  
NCBI Official Synonym Symbols:HADAT1  
NCBI Protein Information:tRNA-specific adenosine deaminase 1
UniProt Protein Name:tRNA-specific adenosine deaminase 1
UniProt Synonym Protein Names:tRNA-specific adenosine-37 deaminase
Protein Family:tRNA-specific adenosine deaminase
UniProt Gene Name:ADAT1  
UniProt Entry Name:ADAT1_HUMAN
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