Description
| Product Name: | Human ADAT1 Recombinant Protein |
| Product Code: | RPPB5789 |
| Size: | 10µg |
| Species: | Human |
| Target: | ADAT1 |
| Synonyms: | tRNA-specific adenosine deaminase 1, hADAT1, tRNA-specific adenosine- 37 deaminase, ADAT1, ADAT-1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | Adenosine Deaminase tRNA-Specific-1 at 0.1mg/ml, 10mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.
Adenosine Deaminase tRNA-Specific 1 Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing amino acids 1-502 and having a total molecular mass of 57.7 kda. ADAT-1 contains T7 tag at N-terminus. ADAT1 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ADAT1: Specifically deaminates adenosine-37 to inosine in tRNA- Ala. Belongs to the ADAT1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA processing; EC 3.5.4.34; HydrolaseChromosomal Location of Human Ortholog: 16q23.1Molecular Function: RNA binding; tRNA-specific adenosine deaminase activityBiological Process: tRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] |
| UniProt Code: | Q9BUB4 |
| NCBI GenInfo Identifier: | 74733201 |
| NCBI Gene ID: | 23536 |
| NCBI Accession: | Q9BUB4.1 |
| UniProt Secondary Accession: | Q9BUB4,Q9NVB7, Q9UNG3 |
| UniProt Related Accession: | Q9BUB4 |
| Molecular Weight: | 38,706 Da |
| NCBI Full Name: | tRNA-specific adenosine deaminase 1 |
| NCBI Synonym Full Names: | adenosine deaminase, tRNA specific 1 |
| NCBI Official Symbol: | ADAT1�� |
| NCBI Official Synonym Symbols: | HADAT1�� |
| NCBI Protein Information: | tRNA-specific adenosine deaminase 1 |
| UniProt Protein Name: | tRNA-specific adenosine deaminase 1 |
| UniProt Synonym Protein Names: | tRNA-specific adenosine-37 deaminase |
| Protein Family: | tRNA-specific adenosine deaminase |
| UniProt Gene Name: | ADAT1�� |
| UniProt Entry Name: | ADAT1_HUMAN |
