HSD17B14 Antibody (PACO40230)
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주문- SKU:
- PACO40230
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | HSD17B14 Antibody (PACO40230) |
Antibody SKU: | PACO40230 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human 17-beta-hydroxysteroid dehydrogenase 14 protein (1-270AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: HSD17B14 antibody at 2µg/ml + Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 29 kDa. Observed band size: 29 kDa. |
Background: | Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro). |
Synonyms: | 17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3) (Short chain dehydrogenase/reductase family 47C member 1), HSD17B14, DHRS10 SDR3 SDR47C1 |
UniProt Protein Function: | HSD17B14: Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family.Protein type: EC 1.1.1.-; OxidoreductaseChromosomal Location of Human Ortholog: 19q13.33Cellular Component: cytosolMolecular Function: estradiol 17-beta-dehydrogenase activity; identical protein binding; protein binding; testosterone 17-beta-dehydrogenase (NADP+) activityBiological Process: estrogen biosynthetic process; steroid catabolic process |
UniProt Protein Details: | |
NCBI Summary: | 17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009] |
UniProt Code: | Q9BPX1 |
NCBI GenInfo Identifier: | 59889578 |
NCBI Gene ID: | 51171 |
NCBI Accession: | NP_057330.2 |
UniProt Secondary Accession: | Q9BPX1,Q9UKU3 |
UniProt Related Accession: | Q9BPX1 |
Molecular Weight: | 44.3kD |
NCBI Full Name: | 17-beta-hydroxysteroid dehydrogenase 14 |
NCBI Synonym Full Names: | hydroxysteroid 17-beta dehydrogenase 14 |
NCBI Official Symbol: | HSD17B14 |
NCBI Official Synonym Symbols: | DHRS10; SDR47C1; retSDR3 |
NCBI Protein Information: | 17-beta-hydroxysteroid dehydrogenase 14 |
UniProt Protein Name: | 17-beta-hydroxysteroid dehydrogenase 14 |
UniProt Synonym Protein Names: | 17-beta-hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase SDR family member 10; Retinal short-chain dehydrogenase/reductase retSDR3; Short chain dehydrogenase/reductase family 47C member 1 |
Protein Family: | 17-beta-hydroxysteroid dehydrogenase |
UniProt Gene Name: | HSD17B14 |
UniProt Entry Name: |
Antibodies |
HSD17B14 Antibody (PACO09808) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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