Description
Golimumab ELISA Kit
The Golimumab ELISA Kit (SKU: GXEL00038) enables sensitive, reproducible quantitative detection of Golimumab in Plasma, Serum using a quantitative ELISA format. The assay delivers a detection range of 62.5 - 4, 000 ng/mL and a sensitivity of 40.1 ng/mL and is read colorimetrically at 450 nm, making it well suited to quantitative research workflows.
Golimumab (Simponi®) is a human immunoglobulin G1? monoclonal antibody which is specific for pro-inflammatory cytokine, tumor necrosis factor-a (TNFa). In 2009, it was approved by FDA for the treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis in adult patients. Elevated levels of TNF are found in the synovial fluid of rheumatoid arthritis, including juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis patients and play an important role in both the pathologic inflammation and the joint destruction that are hallmarks of these diseases. Increased levels of TNF are also found in psoriasis (Ps) plaques. Golimumab binds to both the soluble and transmembrane bioactive forms of human TNF and prevent TNF from binding to its receptors and finally inhibits biological activity of TNF.
Supplied with pre-coated microplates and all core reagents, the Golimumab ELISA Kit gives you a validated, ready-to-use solution for Golimumab research. Get accurate and reliable results with the Golimumab ELISA Kit from Assay Genie.
| Product Name: | Golimumab ELISA Kit |
| SKU: | GXEL00038 |
| Accession: | P01375 |
| Alternative Names: | CNTO 148, 476181-74-5 |
| Assay Type: | Quantitative |
| Detection Method: | Colorimetric |
| Sensitivity: | 40.1 ng/mL |
| Range: | 62.5 - 4, 000 ng/mL |
| Sample Type: | Plasma, Serum |
| Storage: | 2-8°C. See Storage & Stability for details. |
| Note: | For Research Use Only. Not for diagnostic procedures. |
| Parameter | Specification |
|---|---|
| Assay Type | Quantitative |
| Detection Method | Colorimetric |
| Sensitivity | 40.1 ng/mL |
| Detection Range | 62.5 - 4, 000 ng/mL |
| Recovery | 80-120% |
| Sample Types | Plasma, Serum |
When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20°C, the rest reagents should be store at 4°C.
Store the kit at 2-8°C on receipt. Avoid repeated freeze-thaw cycles.
