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  • λΈ”λ‘œκ·Έλ₯Ό ν•˜λ‹€
  • λ©΄μ—­ μš”λ²•

λΈ”λ‘œκ·Έλ₯Ό ν•˜λ‹€

Understanding Myeloid Cell Networks in Cancer Immunotherapy

μ•” λ©΄μ—­ μš”λ²•μ—μ„œ 골수 세포 λ„€νŠΈμ›Œν¬ μ΄ν•΄ν•˜κΈ°λ©΄μ—­ μš”λ²•μ€ μ•” μΉ˜λ£Œμ— ν˜μ‹ μ„ κ°€μ Έμ™”μ§€λ§Œ, 치료 ν›„ μ›λž˜μ˜ λ©΄μ—­ λ°˜μ‘μ„ μž¬ν™•λ¦½ν•˜λŠ” 데 κ·Έ νš¨κ³ΌλŠ” μ œν•œμ μž…λ‹ˆλ‹€. 이 κΈ°μ‚¬λŠ” 골수 세포 λ„€νŠΈμ›Œν¬κ°€ 이 κ³Όμ •μ—μ„œ μ€‘μš”ν•œ 역할을 ν•˜λŠ” 방법을 μ‘°μ‚¬ν•˜λ©°, λ©΄μ—­ μš”λ²• κ²°κ³Όλ₯Ό κ°œμ„ ν•  수 μžˆλŠ” 잠재적인 경둜λ₯Ό κ°•μ‘°ν•©λ‹ˆλ‹€.μ„œλ‘ κ³¨μˆ˜ μ„Έν¬λŠ” λ©΄μ—­ μ‹œμŠ€ν…œμ˜ μ€‘μš”ν•œ ꡬ성 μš”μ†Œλ‘œ, μ•” λ©΄μ—­ μš”λ²•μ—μ„œ κ·Έ 역할이 μ£Όλͺ©λ°›κ³  μžˆμŠ΅λ‹ˆλ‹€. 이 세포듀은 λŒ€μ‹μ„Έν¬, μˆ˜μ§€μƒμ„Έν¬, 과립ꡬλ₯Ό ν¬ν•¨ν•˜λ©°, λ©΄μ—­ λ°˜μ‘μ„ μ‘°μ ˆν•˜λŠ” 데 μ€‘μš”ν•œ 역할을 ν•©λ‹ˆλ‹€. 골수 세포가 ν˜•μ„±ν•˜λŠ” λ³΅μž‘ν•œ λ„€νŠΈμ›Œν¬λ₯Ό μ΄ν•΄ν•˜λŠ” 것은 이듀이 μ•” 치료의 효λŠ₯에 λ―ΈμΉ˜λŠ” 영ν–₯을 ν†΅μ°°ν•˜λŠ” 데 도움이 될 수 μžˆμŠ΅λ‹ˆλ‹€. 이 κΈ°μ‚¬λŠ” 골수 세포 λ„€νŠΈμ›Œν¬κ°€ μ•” 치료 ν›„ λ©΄μ—­ λ°˜μ‘μ˜ μž¬ν™•λ¦½μ„ μ–΄λ–»κ²Œ μ§€λ°°ν•˜λŠ”μ§€λ₯Ό μ„€λͺ…ν•˜λŠ” 졜근 연ꡬ κ²°κ³Όλ₯Ό λ‹€λ£Ήλ‹ˆλ‹€.λ©΄μ—­ μ‹œμŠ€ν…œμ—μ„œμ˜ 골수 μ„Έν¬μ˜ μ—­ν• κ³¨μˆ˜ μ„Έν¬λŠ” 골수의 쑰혈 쀄기 μ„Έν¬μ—μ„œ μœ λž˜ν•˜λ©°, μ„ μ²œμ  및 적응 λ©΄μ—­ λͺ¨λ‘μ— ν•„μˆ˜μ μž…λ‹ˆλ‹€. 이듀은 병원체에 λŒ€ν•œ 첫 번째 λ°©μ–΄μ„  역할을 ν•˜λ©°, μ’…μ–‘ λ―Έμ„Έ ν™˜κ²½μ—μ„œ μ€‘μš”ν•œ 역할을 ν•©λ‹ˆλ‹€. 골수 μ„Έν¬λŠ” λ‹€μ–‘ν•œ μ•„ν˜•μœΌλ‘œ λΆ„ν™”ν•  수 있으며, 각 μ•„ν˜•μ€ 항원 μ œμ‹œ, 식세포 μž‘μš©, 사이토카인 λΆ„λΉ„ λ“± λ‹€μ–‘ν•œ κΈ°λŠ₯을 μˆ˜ν–‰ν•©λ‹ˆλ‹€. μ΄λ“€μ˜ κ°€μ†Œμ„±μ€ λ‹€μ–‘ν•œ λ―Έμ„Έ ν™˜κ²½μ— 적응할 수 있게 ν•˜λ©°, μ΄λŠ” μ•”μ˜ λ§₯λ½μ—μ„œ 특히 μ€‘μš”ν•©λ‹ˆλ‹€.연ꡬ μš”μ•½Dangaj와 Mac Fhearraigh …
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21st Aug 2025 SeΓ‘n Mac Fhearraigh, PhD
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