Anti-VEGF-D Antibody (CAB19242)

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SKU:
CAB19242
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
VEGFD
Synonyms:
FIGF
Synonyms:
VEGF-D
Synonyms:
vascular endothelial growth factor D
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Description

Product Name:VEGF-D Rabbit mAb
Product Code:CAB19242
Size:20uL, 50uL, 100uL
Synonyms:VEGFD, FIGF, VEGF-D, vascular endothelial growth factor D
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human VEGF-D .
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HT-29, A-549, NCI-H460, H9C2, Mouse lung, Mouse heart, Rat heart
Immunogen:Recombinant protein of human VEGF-D .
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:2277
Uniprot:O43915
Cellular Location:Secreted
Calculated MW:40kDa
Observed MW:41KDa
UniProt Protein Function:VEGFD: Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Belongs to the PDGF/VEGF growth factor family.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: Xp22.31

Cellular Component: extracellular region

Molecular Function:chemoattractant activity; platelet-derived growth factor receptor binding; vascular endothelial growth factor receptor binding

Biological Process: induction of positive chemotaxis; platelet degranulation; vascular endothelial growth factor receptor signaling pathway

NCBI Summary:The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]
UniProt Code:O43915
NCBI GenInfo Identifier:17367984
NCBI Gene ID:2277
NCBI Accession:O43915.1
UniProt Secondary Accession:O43915,B2R7Z3,
UniProt Related Accession:O43915
Molecular Weight:40,444 Da
NCBI Full Name:Vascular endothelial growth factor D
NCBI Synonym Full Names:c-fos induced growth factor
NCBI Official Symbol:FIGF  
NCBI Official Synonym Symbols:VEGFD; VEGF-D  
NCBI Protein Information:vascular endothelial growth factor D
UniProt Protein Name:Vascular endothelial growth factor D
UniProt Synonym Protein Names:c-Fos-induced growth factor; FIGF
UniProt Gene Name:FIGF  
UniProt Entry Name:VEGFD_HUMAN
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