Anti-NAT10 Antibody (CAB19286)

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주문
SKU:
CAB19286
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
NAT10
Synonyms:
ALP
Synonyms:
NET43
Synonyms:
Kre33
Synonyms:
N-acetyltransferase 10
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Description

Product Name:NAT10 Rabbit mAb
Product Code:CAB19286
Size:20uL, 50uL, 100uL
Synonyms:NAT10, ALP, NET43, Kre33, N-acetyltransferase 10
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human NAT10.
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, K-562, SH-SY5Y, Mouse testis
Immunogen:Recombinant protein of human NAT10.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:55226
Uniprot:Q9H0A0
Cellular Location:Nucleus, nucleolus
Calculated MW:116kDa
Observed MW:120KDa
UniProt Protein Function:ALP: Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division. Belongs to the UPF0202 family.
UniProt Protein Details:

Protein type:EC 2.3.1.-; Acetyltransferase; Nucleolus

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: membrane; nucleolus; nucleus

Molecular Function:N-acetyltransferase activity; ATP binding

Biological Process: metabolic process

NCBI Summary:The protein encoded by this gene is an RNA cytidine acetyltransferase involved in histone acetylation, tRNA acetylation, the biosynthesis of 18S rRNA, and the enhancement of nuclear architecture and chromatin organization. [provided by RefSeq, Oct 2016]
UniProt Code:Q9H0A0
NCBI GenInfo Identifier:313104140
NCBI Gene ID:55226
NCBI Accession:Q9H0A0.2
UniProt Related Accession:Q9H0A0
Molecular Weight:
NCBI Full Name:RNA cytidine acetyltransferase
NCBI Synonym Full Names:N-acetyltransferase 10
NCBI Official Symbol:NAT10  
NCBI Official Synonym Symbols:ALP; Kre33; NET43  
NCBI Protein Information:RNA cytidine acetyltransferase
UniProt Protein Name:N-acetyltransferase 10
Protein Family:Putative nucleobase-ascorbate transporter
UniProt Gene Name:NAT10  
UniProt Entry Name:NAT10_HUMAN
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