The TRIM49 Polyclonal Antibody (PAC017257) is a valuable tool for researchers studying TRIM49, a protein that plays a role in immune regulation and response. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blotting applications.TRIM49 is involved in various cellular processes, including immune signaling and inflammation. Research suggests that TRIM49 may play a role in regulating immune responses, making it a potential target for studying diseases related to immune dysfunction.
By using the TRIM49 Polyclonal Antibody, researchers can detect and analyze TRIM49 protein in different cell types, aiding in the understanding of its function in immunology and disease. This antibody is ideal for studies focusing on immune regulation, autoimmune disorders, and inflammatory conditions, providing valuable insights into potential therapies targeting TRIM49.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17257(TRIM49 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO17257(TRIM49 Antibody) at dilution 1/800 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17257(TRIM49 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This gene has been found to be preferentially expressed in testis. Related pseudogenes and gene duplicates have also been identified on chromosome 11.
Synonyms:
tripartite motif containing 49
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This gene has been found to be preferentially expressed in testis. Related pseudogenes and gene duplicates have also been identified on chromosome 11. [provided by RefSeq, Aug 2010]
