The TMPRSS6 Rabbit Polyclonal Antibody is a valuable tool for researchers studying the transmembrane protease serine 6 (TMPRSS6) protein. TMPRSS6 is involved in iron homeostasis and regulation of hepcidin, making it a key player in iron metabolism and related disorders such as iron-deficiency anemia. This antibody, raised in rabbits, is highly specific to TMPRSS6 and is validated for use in various applications, including Western blot and immunohistochemistry.
By binding to TMPRSS6, researchers can accurately detect and analyze this critical protein in different cell types and tissues.Understanding the role of TMPRSS6 is essential for advancing research in hematology, iron metabolism, and related diseases. The TMPRSS6 Rabbit Polyclonal Antibody provides a reliable tool for investigators looking to explore the functions and mechanisms of TMPRSS6 in various physiological and pathological conditions.
Product Name:
TMPRSS6 Polyclonal Antibody
SKU:
CAB10642
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 77-220 of human TMPRSS6 (NP_705837.1).
Cell membrane, Single-pass type II membrane protein.
Calculated MW:
90kDa
Observed MW:
110kDa
The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
164656
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TMPRSS6 antibody (CAB10642) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
