The TMEM26 Polyclonal Antibody (PACO59912) is a valuable tool for researchers studying TMEM26, a transmembrane protein associated with immune function and inflammation. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the TMEM26 protein, this antibody allows for the detection and analysis of TMEM26 in a variety of cell types, making it an ideal choice for studies in immunology and inflammatory disease research.
TMEM26, also known as a potential immune regulator, is involved in immune system modulation and inflammatory responses. Its role in regulating immune function and inflammation makes it an attractive target for research in diseases such as autoimmune disorders, infectious diseases, and inflammatory conditions. Understanding the function of TMEM26 is essential for developing targeted therapies that modulate immune responses and alleviate inflammation in these disease contexts.
Antibody Name:
TMEM26 Antibody (PACO59912)
Antibody SKU:
PACO59912
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Transmembrane protein 26 protein (302-368AA)
Immunofluorescence staining of A549 cells with PACO59912 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
Transmembrane protein 26, TMEM26
UniProt Protein Function:
TMEM26: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 10q21.2Cellular Component: integral to membrane
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein containing multiple transmembrane helices. It is a selective surface protein marker of brite/beige adipocytes, which may coexist with classical brown adipocytes in brown adipose tissue. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
