The TCP11 Monoclonal Antibody (PACO12682) is a powerful tool for researchers studying TCP11, a protein involved in sperm maturation and fertility. This monoclonal antibody, produced using hybridoma technology, is highly specific to human samples and is suitable for various applications, including Western blot, immunohistochemistry, and flow cytometry.TCP11 is known to play a crucial role in spermatogenesis, specifically in the development and function of sperm cells.
Dysregulation of TCP11 has been linked to male infertility and reproductive disorders, making it an important target for studies in reproductive biology and fertility research. This antibody's ability to specifically detect TCP11 protein allows for detailed analysis and localization of TCP11 in different cell types, providing valuable insights into its function and potential therapeutic implications.
TCP11: a T-complex protein. Important in sperm function and fertility. Encodes the receptor for fertilization-promoting peptide (FPP). FPP (pGlu-Glu-ProNH2) is a peptide produced by the prostate gland and secreted into seminal plasma. The addition of FPP to uncapacitated sperm suspensions stimulates capacitation as demonstrated by increased fertilizing/penetrating ability.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p21.31Cellular Component: integral to membraneBiological Process: multicellular organismal development; spermatogenesis; cell differentiation
