The SPRR2A Polyclonal Antibody (PAC038954) is specifically designed for research involving SPRR2A, a protein associated with epidermal differentiation and skin barrier function. This antibody, derived from rabbit hosts, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting. By binding to the SPRR2A protein, this antibody facilitates the detection and analysis of SPRR2A expression in different cell types, making it an excellent tool for studies focused on skin biology and dermatological research.SPRR2A is known to play a crucial role in maintaining skin integrity and protecting against environmental stressors.
Its involvement in epidermal differentiation processes underscores its relevance in skin health and disease. Research into SPRR2A function is essential for gaining insights into skin barrier function and developing therapeutic strategies for skin conditions such as dermatitis, psoriasis, and atopic eczema. By studying the role of SPRR2A, researchers can advance our understanding of skin biology and potentially uncover new targets for skincare treatments.
Antibody Name:
SPRR2A Antibody (PACO38954)
Antibody SKU:
PACO38954
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Small proline-rich protein 2A protein (1-72AA)
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Synonyms:
Small proline-rich protein 2A (SPR-2A) (2-1), SPRR2A
UniProt Protein Function:
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
