The SNRNP48 Polyclonal Antibody (PACO36874) is a valuable tool for researchers studying the protein SNRNP48, a crucial component of the spliceosome complex involved in RNA splicing. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. Its specificity for SNRNP48 enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and genetic research.
SNRNP48 is essential for spliceosome assembly and function, playing a vital role in pre-mRNA splicing and gene expression regulation. Mutations or dysregulation of SNRNP48 have been linked to various diseases, including genetic disorders and cancer, highlighting its importance in cellular processes. By targeting SNRNP48 with this polyclonal antibody, researchers can gain insights into its function and potential therapeutic implications in disease pathology and treatment strategies.
Antibody Name:
SNRNP48 Antibody (PACO36874)
Antibody SKU:
PACO36874
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human U11/U12 small nuclear ribonucleoprotein 48 kDa protein (1-300AA)
Likely involved in U12-type 5' splice site recognition.
Synonyms:
U11/U12 small nuclear ribonucleoprotein 48 kDa protein (U11/U12 snRNP 48 kDa protein) (U11/U12-48K), SNRNP48, C6orf151
UniProt Protein Function:
SNRNP48: Likely involved in U12-type 5' splice site recognition. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA splicingChromosomal Location of Human Ortholog: 6p24.3Cellular Component: nucleoplasm; cytoplasm; U12-dependent spliceosomeMolecular Function: metal ion bindingBiological Process: RNA splicing; mRNA processing
