The SLC27A3 Polyclonal Antibody (PAC012277) is specifically designed for research involving SLC27A3, a key protein involved in lipid metabolism and fatty acid uptake. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By detecting and binding to the SLC27A3 protein, researchers can study its role in cellular pathways related to lipid metabolism, making it a valuable tool for studies in metabolic disorders, obesity, and related diseases.SLC27A3, also known as fatty acid transport protein 3 (FATP3), plays a crucial role in the transport and uptake of long-chain fatty acids in cells. Dysregulation of SLC27A3 has been linked to metabolic disorders and diseases like non-alcoholic fatty liver disease (NAFLD) and insulin resistance.
Understanding the function of SLC27A3 can provide insights into the pathogenesis of these conditions and potentially lead to the development of targeted therapies for metabolic disorders.Overall, the SLC27A3 Polyclonal Antibody is a valuable tool for researchers studying lipid metabolism and related diseases, offering high specificity and sensitivity in detecting SLC27A3 protein levels in various cell types and tissues. Its use can contribute to advances in our understanding of metabolic processes and the development of novel therapeutic strategies for metabolic disorders.
solute carrier family 27 (fatty acid, transporter), member 3;SLC27A3;ACSVL3;FATP3;MGC4365;VLCS-3 ;
UniProt Protein Function:
SLC27A3: Has acyl-CoA ligase activity for long-chain and very- long-chain fatty acids. Does not exhibit fatty acid transport activity. Belongs to the ATP-dependent AMP-binding enzyme family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 6.2.1.-; Membrane protein, integral; Mitochondrial; Ligase; Membrane protein, multi-passChromosomal Location of Human Ortholog: 1q21.3Cellular Component: membrane