SIRPB1 Antibody (PACO12218)
- SKU:
- PACO12218
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SIRPB1 Antibody (PACO12218) |
| Antibody SKU: | PACO12218 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human SIRPB1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | signal-regulatory protein β 1;SIRPB1;CD172b;DKFZp686A05192;FLJ26614;SIRP-BETA-1 ; |
| UniProt Protein Function: | SIRPB1 iso3: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 20p13Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: protein bindingBiological Process: cell surface receptor linked signal transduction; innate immune response; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] |
| UniProt Code: | Q5TFQ8 |
| NCBI GenInfo Identifier: | 205829937 |
| NCBI Gene ID: | 10326 |
| NCBI Accession: | Q5TFQ8.1 |
| UniProt Secondary Accession: | Q5TFQ8,Q7Z3B9 |
| UniProt Related Accession: | Q5TFQ8, O00241 |
| Molecular Weight: | 43,211 Da |
| NCBI Full Name: | Signal-regulatory protein beta-1 isoform 3 |
| NCBI Synonym Full Names: | signal regulatory protein beta 1 |
| NCBI Official Symbol: | SIRPB1 |
| NCBI Official Synonym Symbols: | CD172b; SIRP-BETA-1 |
| NCBI Protein Information: | signal-regulatory protein beta-1 |
| UniProt Protein Name: | Signal-regulatory protein beta-1 isoform 3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Signal-regulatory protein |
| UniProt Gene Name: | SIRPB1 |
| UniProt Entry Name: | SIRBL_HUMAN |
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