The SEC16A Polyclonal Antibody (PACO05840) is a valuable tool for researchers studying SEC16A, a protein involved in protein trafficking and secretion in cells. This antibody, raised in rabbits, is highly specific to human SEC16A and has been validated for use in Western blot applications. By binding to the SEC16A protein, this antibody allows for the detection and analysis of SEC16A in a variety of cell types, making it ideal for studies in cell biology and molecular biology.SEC16A plays a crucial role in the regulation of protein transport from the endoplasmic reticulum to the Golgi apparatus, making it essential for proper cellular function.
Research on SEC16A is important for understanding cellular processes such as protein synthesis and secretion, as well as for investigating diseases related to protein trafficking dysfunction. The SEC16A Polyclonal Antibody is a valuable tool for researchers looking to uncover the mechanisms by which SEC16A contributes to cellular homeostasis and disease pathology.
Antibody Name:
SEC16A Antibody (PACO05840)
Antibody SKU:
PACO05840
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:20000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human Sec16A.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
SEC16A; KIAA0310; SEC16; SEC16L; Protein transport protein Sec16A; SEC16 homolog A
UniProt Protein Function:
Defines endoplasmic reticulum exit sites (ERES) and is required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for normal transitional endoplasmic reticulum (tER) organization.
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013]
