Recombinant Mouse Prostaglandin-H2 D-isomerase/PTGDS Protein (RPCB1860)
- SKU:
- RPCB1860
- Size:
- 100µg
- Tag:
- C-His
- Reactivity:
- Mouse
- Expression Host:
- HEK293 Cells
Description
| Product Name: | Recombinant Mouse Prostaglandin-H2 D-isomerase/PTGDS Protein |
| SKU: | RPCB1860 |
| Size: | 100µg |
| Tag: | C-His |
| Reactivity: | Mouse |
| Expression Host: | HEK293 Cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse Prostaglandin-H2 D-isomerase/PTGDS Protein , tested reactivity in HEK293 Cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <1EU/μg |
| Purity: | > 95% by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 19215 |
PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of PGH2 to PGD2. It is involved in smooth muscle contraction/relaxation and a variety of central nervous system functions. PTGDS may have an anti-apoptotic role in oligodendrocytes. It binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | O09114 |
 | Recombinant Mouse Prostaglandin- H2 D-isomerase/PTGDS Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 28-32 kDa. |
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