Recombinant Mouse EGFR/HER1 Protein (RPCB1995)
- SKU:
- RPCB1995
- Size:
- 10µg
- Tag:
- C-6His
- Reactivity:
- Mouse
- Expression Host:
- HEK293 cells
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Description
| Product Name: | Recombinant Mouse EGFR/HER1 Protein |
| SKU: | RPCB1995 |
| Size: | 10µg |
| Tag: | C-6His |
| Reactivity: | Mouse |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse EGFR/HER1 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <1EU/ug of the protein by LAL method. |
| Purity: | > 95% by Tris-Bis PAGE and HPLC. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 13649 |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q01279 |
 | Recombinant Mouse IL-21 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 100-140kDa. |
 | The purity of Mouse EGFR is greater than 95% as determined by SEC- HPLC. |
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