Recombinant Human UBE2L3 Protein (RPCB0163)
- SKU:
- RPCB0163
- Size:
- 50µg
- Tag:
- C-His
- Reactivity:
- Human
- Expression Host:
- E. coli
Description
| Product Name: | Recombinant Human UBE2L3 Protein |
| SKU: | RPCB0163 |
| Size: | 50µg |
| Tag: | C-His |
| Reactivity: | Human |
| Expression Host: | E. coli |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human UBE2L3 Protein , tested reactivity inE. coliand has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | Please contact us for more information. |
| Purity: | > 95% by SDS-PAGE. |
| Formulation: | Supplied in 50mM HEPES，200mM NaCl，10%glycerol，1mM TCEP，pH 7.0Contact us for customized product form or formulation. |
| Gene ID: | 7332 |
Ubiquitin-conjugating Enzyme E2L 3 (UBE2L3),also known as Ubiquitin-conjugating Enzyme H7 (UbcH7), is a member of the Ubiquitin-conjugating (E2) enzyme family (1). The human UbcH7 protein shares 100% amino acid (aa) sequence identity with the mouse and rat orthologs. UBE2L3 is catalytically active with HECT and RBR domain-containing families of Ubiquitin ligases (E3s). UBE2L3 localizes to both the nucleus and cytoplasm in human cells. UBE2L3 depletion results in an extended S phase and a reduced rate of proliferation, suggesting that it may play a role in the cell cycle. In humans, single nucleotide polymorphisms in UBE2L3 are associated with systemic lupus erythematosus and Crohn's disease, suggesting that UbcH7 is important for proper immune system function.
| Storage: | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
| Swiss-Prot: | P68036 |
 | Recombinant Human UBE2L3 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 19 kDa. |
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