Recombinant Human STAR Protein(Sumo Tag) (RPES8009)
- SKU:
- RPES8009
- Size:
- 20μg
- Tag:
- N-Sumo
- Reactivity:
- Human
- Expression Host:
- E.coli
- Accession:
- P49675
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Description
| Product Name: | Recombinant Human STAR Protein (Sumo Tag) |
| SKU: | RPES8009 |
| Size: | 20μg |
| Tag: | N-Sumo |
| Reactivity: | Human |
| Expression Host: | E.coli |
| Accession: | P49675 |
| Sequence: | Met1-Cys285 |
| Calculated Molecular Weight: | 44.2 kDa |
| Observed Molecular Weight: | 45-50 kDa |
| Synonyms: | Cholesterol trafficker, Luteinizing hormone induced protein, mitochondrial, Mitochondrial steroid acute regulatory protein, StAR, StAR related lipid transfer (START) domain containing 1, STAR, StARD1, START domain containing 1, START domain containing protein 1, START domain-containing protein 1, Steroid acute regulatory protein, Steroidogenic acute regulator, Steroidogenic acute regulatory protein, Steroidogenic acute regulatory protein mitochondrial |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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