Recombinant Human Notch 3 Protein (RPCB2180)
- SKU:
- RPCB2180
- Size:
- 100µg
- Tag:
- C-His&Avi
- Reactivity:
- Human
- Expression Host:
- HEK293 cells
Frequently bought together:
Description
| Product Name: | Recombinant Human Notch 3 Protein |
| SKU: | RPCB2180 |
| Size: | 100µg |
| Tag: | C-His&Avi |
| Reactivity: | Human |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human Notch 3 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | Less than 1EU per μg by the LAL method. |
| Purity: | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
| Gene ID: | 4854 |
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q9UM47 |
 | Human Notch 3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
 | The purity of Human Notch 3 is greater than 95% as determined by SEC-HPLC. |
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