Recombinant Human/Mouse/Rat mature BMP-2 Protein (RPCB1593)
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- SKU:
- RPCB1593
- Size:
- 10µg
- Tag:
- No tag
- Reactivity:
- Human
Frequently bought together:
Description
| Product Name: | Recombinant Human/Mouse/Rat mature BMP-2 Protein |
| SKU: | RPCB1593 |
| Size: | 10µg |
| Tag: | No tag |
| Reactivity: | Human |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human/Mouse/Rat mature BMP-2 Protein , tested reactivity in E.coli and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method. |
| Purity: | > 95% by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of 0.1% TFA, 30% ACN. Contact us for customized product form or formulation. |
| Gene ID: | 650 |
BMP-2 like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is also involved in cardiac cell differentiation and epithelial to mesenchymal transition. Like many other proteins from the BMP family, BMP-2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2 may be involved in white adipogenesis and may have metabolic effects.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P12643 |
 | Recombinant Human/Mouse/Rat mature BMP-2 Protein was resolved with SDS PAGE under reducing (R) and non-reducing (NR) conditions ，showing single bands at 15-20 kDa and 25-30 kDa, respectively. |
 | Recombinant Human/Mouse/Rat mature BMP-2 Protein induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED₅₀ for this effect is 24.59-98.36 ng/mL, corresponding to a specific activity of 1.02×104~4.07×104 units/mg. |
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