Recombinant Human MMP-8 Protein (RPCB1565)
- SKU:
- RPCB1565
- Size:
- 10µg
- Tag:
- C-His
- Reactivity:
- Human
- Expression Host:
- HEK293 cells
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Description
| Product Name: | Recombinant Human MMP-8 Protein |
| SKU: | RPCB1565 |
| Size: | 10µg |
| Tag: | C-His |
| Reactivity: | Human |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human MMP-8 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <0.01EU/μg by the LAL method. |
| Purity: | > 95% as determined by Tris-Bis PAGE |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of 50mM Tris , 10 mM CaCl2，150 mM NaCl, pH 7.5. Contact us for customized product form or formulation. |
| Gene ID: | 4317 |
Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was significantly associated with low HCS.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P22894 |
 | Recombinant Human MMP-8 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 60-75kDa. |
 | The purity of Human MMP-8 is greater than 95% as determined by SEC-HPLC. |
 | Recombinant Human MMP-8 Protein cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (RD,Catalog # ES001). The specific activity is >194 pmol/min/µg, as measured under the described conditions. |
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