Recombinant Human IL2RA Protein (Fc Tag) (RPES8321)
- SKU:
- RPES8321
- Size:
- 20μg
- Tag:
- C-Fc
- Reactivity:
- Human
- Expression Host:
- Mammalian
- Accession:
- P01589
Frequently bought together:
Description
| Product Name: | Recombinant Human IL2RA Protein (Fc Tag) |
| SKU: | RPES8321 |
| Size: | 20μg |
| Tag: | C-Fc |
| Reactivity: | Human |
| Expression Host: | Mammalian |
| Accession: | P01589 |
| Sequence: | Glu22-Gln240 |
| Calculated Molecular Weight: | 48.9 kDa |
| Observed Molecular Weight: | 60 kDa |
| Synonyms: | Interleukin 2 receptor alpha chain, CD25, CD25 antigen, IDDM10, IL 2 receptor alpha subunit, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2 RA, IL2-RA, IL2R, IL2R, alpha chain, IL2RA, IL2RA, IMD41, Interleukin 2 receptor alpha, Interleukin 2 receptor, Interleukin-2 receptor subunit alpha, p55, t-cell growth factor receptor, TAC, TAC antigen, TCGFR |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with an the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with an interleukin 2 receptor alpha deficiency.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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