Description
| Product Name: | Recombinant Human Fetuin B Protein (His Tag) |
| SKU: | RPES8350 |
| Size: | 20μg |
| Tag: | C-His |
| Reactivity: | Human |
| Expression Host: | Mammalian |
| Accession: | Q9UGM5 |
| Sequence: | Cys16-Pro382 |
| Calculated Molecular Weight: | 40.3 kDa |
| Observed Molecular Weight: | 55 kDa |
| Synonyms: | 16G, IRL, 16G2, 2310011O17Rik, AI255764, D17980, Fet, Fetuin beta, Fetuin-B, Fetuin-like protein, Fetuin-like protein IRL685, Gugu, IRL685, Pp63, FETUB |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
Fetuin-B , also known as Fetuin-like protein IRL685 and FETUB , is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family , part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions , including osteogenesis and bone resorption. Fetuin-A has been identified as a major protein during fetal life and is also involved in important functions such as protease inhibitory activities and development-associated regulation of calcium metabolism and osteogenesis. Fetuin-A is a key partner in the recovery phase of an acute inflammatory response. Fetuin-B / FETUB is found at least in Human and rodents. It is unambiguously a paralogue of Fetuin-A. Fetuin-A and Fetuin-B exhibit significant differences at the amino acid sequence level , notably including variations with respect to the archetypal fetuin-specific signature.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |