Recombinant Human CEACAM5/CEA/CD66e (145-322) Protein (RPCB0618)
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- SKU:
- RPCB0618
- Size:
- 100µg
- Tag:
- C-His
- Reactivity:
- Human
Frequently bought together:
Description
| Product Name: | Recombinant Human CEACAM5/CEA/CD66e (145-322) Protein |
| SKU: | RPCB0618 |
| Size: | 100µg |
| Tag: | C-His |
| Reactivity: | Human |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human CEACAM5/CEA/CD66e (145-322) Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method |
| Purity: | > 95% by SDS-PAGE；> 95% by HPLC |
| Formulation: | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Gene ID: | 1048 |
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.
| Storage: | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
| Swiss-Prot: | P06731-1 |
 | Human CEACAM-5 (145-322) on Tris- Bis PAGE under reduced condition. The purity is greater than 95%. |
 | The purity of Human CEACAM-5 (145-322) is greater than 95% as determined by SEC-HPLC. |
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