Recombinant Human ApolipoproteinA-IV/APOA4 Protein (RPCB1223)
- SKU:
- RPCB1223
- Size:
- 10µg
- Tag:
- C-His
- Reactivity:
- Human
- Expression Host:
- HEK293 cells
Description
| Product Name: | Recombinant Human ApolipoproteinA-IV/APOA4 Protein |
| SKU: | RPCB1223 |
| Size: | 10µg |
| Tag: | C-His |
| Reactivity: | Human |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human ApolipoproteinA-IV/APOA4 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <0.01EU/μg of the protein by LAL method. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 337 |
Apolipoprotein A-IV (ApoA-IV), first discovered in rat plasma in the 1970s , is a 46 kD glycoprotein with relatively high concentrations in plasma (15–37 mg/dL) . It is expressed predominantly in the mammalian small intestine (with highest expression in the duodenum), and also expressed in rodent liver at lower levels. Sensing lipid absorption in enterocytes , ApoA-IV is synthesized and packaged with lipids and other apolipoproteins into chylomicrons and secreted through the lymphatic system into the blood. Once there, as a member of exchangeable apolipoproteins, ApoA-IV dissociates from chylomicrons and transfers to HDL (high density lipoprotein) particles or circulates in lipid-free form .ApoA-IV may protect against atherosclerosis , mediate reverse cholesterol transport , act as an anti-inflammatory agent and modulate intestinal lipid absorption .
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P06727 |
 | Recombinant Human ApolipoproteinA-IV/APOA4 Protein was determined by SDS-PAGE with Coomassie Blue, showing bands at 45-55 kDa. |
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Human Apolipoprotein A-IV (APOA4) ELISA Kit (HUEB0299)
