Recombinant Human Angiopoietin-1/ANG1 (N-Fc) (RPES6305)

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SKU:
RPES6305
Product Type:
Recombinant Protein
Species:
Human
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Description

Product Name:Recombinant Human Angiopoietin-1/ANG1 (N-Fc)
Product Code:RPES6305
Size:10µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, Angiopoietin-1, ANGPT1
Mol Mass:53.9 kDa
AP Mol Mass:55-65 kDa
Tag:N-Fc
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Asp256-Phe498
Accession:Q15389
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.

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