Description
| Product Name: | Recombinant Cynomolgus B7-2/CD86 Protein |
| SKU: | RPCB1580 |
| Size: | 100µg |
| Tag: | C-His |
| Reactivity: | Cynomolgus |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Cynomolgus B7-2/CD86 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | Less than 1EU per μg by the LAL method. |
| Purity: | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | G7NXR4 |
 | Cynomolgus B7-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
 | The purity of Cynomolgus B7-2 is greater than 95% as determined by SEC-HPLC. |
