The Rabbit Control IgG (CABC005) is a high-quality polyclonal antibody suitable for research involving CD300A, an immune inhibitory receptor crucial for immune regulation. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for Western blot applications. By specifically binding to the CD300A protein, researchers can effectively detect and analyze its presence in various cell types, making it an essential tool for studies in immunology and cancer research.CD300A plays a vital role in immune homeostasis by modulating inflammation and inhibiting allergic reactions.
Its significance in immune response modulation makes it a valuable target for research into diseases like cancer, autoimmune disorders, and chronic inflammatory conditions. A thorough understanding of the activity of CD300A is essential for developing innovative therapies that can harness or modulate immune function in these contexts. The Rabbit Control IgG (CABC005) provides researchers with a reliable tool to study the functions and mechanisms of CD300A, ultimately contributing to advancements in the field of immunology and cancer research.
Product Name:
Rabbit Control IgG
SKU:
CABC005
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Tested Applications:
IPChIP
Recommended Dilution:
IP,0.5ug-4ug antibody for 200ug-400ug extracts of whole cellsChIP,5μg antibody for 10μg-15μg of Chromatin
Conjugate:
Unconjugated
The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer.
Purification Method:
Potein A/G purification
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunoprecipitation of over-expressed DDDDK-tagged protein in 293T cells incubated using DDDDK-tag antibody (AE063). Secondary antibody: HRP-conjugated AffiniPure Mouse Anti-Rabbit IgG Light Chain (CABS061).A mock served as negative control using rabbit Control IgG（AC005）and over-expressed 293T cell lysate served as positive control.
