The NDUSF5 Polyclonal Antibody is a valuable tool for research involving the NDUSF5 protein, a key component of the mitochondrial respiratory chain complex I. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to NDUSF5, researchers can accurately detect and analyze the protein in various cell types, making it an excellent choice for studies in mitochondrial biology and related fields.NDUSF5 is essential for the proper function of complex I in the electron transport chain, playing a crucial role in cellular energy production. Dysregulation of NDUSF5 has been implicated in various diseases, including neurological disorders and metabolic conditions.
Investigating the function and expression of NDUSF5 is instrumental in understanding the pathophysiology of these disorders and may lead to the development of targeted therapeutic interventions aimed at restoring mitochondrial function.Overall, the NDUSF5 Polyclonal Antibody offers researchers a reliable tool for exploring the biology of NDUSF5 and its implications in human health and disease. Its specificity and sensitivity make it a valuable asset for advancing knowledge in the field of mitochondrial research.
Product Name:
NDUFS5 Polyclonal Antibody
SKU:
CAB21505
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human NDUFS5 (NP_004543.1).
This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17.
Purification Method:
Affinity purification
Gene ID:
4725
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NDUFS5 antibody (CAB21505) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
![[KD Validated] NDUFS5 Polyclonal Antibody (CAB21504)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/196355/194373/A21504_1__66057__36432.1750794553.jpg?c=1 "[KD Validated] NDUFS5 Polyclonal Antibody (CAB21504)")
