Mouse MDH2 Recombinant Protein (RPPB1931)
- SKU:
- RPPB1931
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Mouse
- Target:
- MDH2
- Synonyms:
- M-MDH
- MDH
- MOR1
- Source:
- Escherichia Coli
- Uniprot:
- P08249
Frequently bought together:
Description
| Product Name: | Mouse MDH2 Recombinant Protein |
| Product Code: | RPPB1931 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | MDH2 |
| Synonyms: | M-MDH, MDH, MOR1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | MDH2 protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4) and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAKVAVLGAS GGIGQPLSLL LKNSPLVSRL TLYDIAHTPG VAADLSHIET RANVKGYLGP EQLPDCLKGC DVVVIPAGVP RKPGMTRDDL FNTNATIVAT LTAACAQHCP EAMVCIIANP VNSTIPITAE VFKKHGVYNP NKIFGVTTLD IVRANTFVAE LKGLDPARVN VPVIGGHAGK TIIPLISQCT PKVDFPQDQL ATLTGRIQEA GTEVVKAKAG AGSATLSMAY AGARFVFSLV DAMNGKEGVV ECSFVQSKET ECTYFSTPLL LGKKGLEKNL GIGKITPFEE KMIAEAIPEL KASIKKGEDF VKNMK |
| Biological Activity: | Specific activity is > 800 units/mg, and is defined as the amount of enzyme that cleaves 1umole of oxaloacetate and beta-NADH to Lmalate and beta-NAD per minute at pH8.0 at 37°C. |
MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highy expressed in the adrenal system, small intestine, heart and pancreas.
MDH2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 335 amino acids (25-338a.a.) and having a molecular mass of 35.4kDa. MDH2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P08249 |
| NCBI GenInfo Identifier: | 146345457 |
| NCBI Gene ID: | 17448 |
| NCBI Accession: | P08249.3 |
| UniProt Secondary Accession: | P08249,Q0QF44, Q8CF79, Q8R1P0 |
| UniProt Related Accession: | P08249 |
| Molecular Weight: | 35,611 Da |
| NCBI Full Name: | Malate dehydrogenase, mitochondrial |
| NCBI Synonym Full Names: | malate dehydrogenase 2, NAD (mitochondrial) |
| NCBI Official Symbol: | Mdh2 |
| NCBI Official Synonym Symbols: | MDH; Mor1; Mdh-2; Mor-1 |
| NCBI Protein Information: | malate dehydrogenase, mitochondrial |
| UniProt Protein Name: | Malate dehydrogenase, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | Malate dehydrogenase |
| UniProt Gene Name: | Mdh2 |
| UniProt Entry Name: |
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