The Mouse CD45.2 Monoclonal Antibody (AF488 Conjugated, 104-2, AGEL1533) from AssayGenie is a highly specific antibody designed for research applications involving CD45.2, a cell surface protein expressed on leukocytes. This monoclonal antibody, conjugated with AF488 for fluorescence detection, is perfect for flow cytometry and immunofluorescence studies. It binds specifically to the CD45.2 protein, allowing for precise detection and analysis in various mouse cell types.CD45.2, also known as leukocyte common antigen, is a crucial marker for immune cell identification and activation status. By targeting CD45.2, researchers can study immune cell populations, monitor immune responses, and investigate leukocyte functions in different experimental settings.
This antibody provides reliable and reproducible results, making it an essential tool for immunologists, cell biologists, and researchers studying immune-related diseases and immune system modulation.With its high specificity and conjugation with AF488 for easy visualization, the Mouse CD45.2 Monoclonal Antibody (AF488 Conjugated, 104-2, AGEL1533) offers a valuable resource for advancing research in immunology, cancer biology, and other fields where immune cell analysis is crucial. Trust AssayGenie's quality product to enhance your studies and gain valuable insights into immune cell dynamics and functions.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
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