Klk7 Antibody (PACO27817)
- SKU:
- PACO27817
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Klk7 Antibody (PACO27817) |
| Antibody SKU: | PACO27817 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Glandular kallikrein-7, submandibular/renal protein (25-261AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Predominant kallikrein protein in the kidney. |
| Synonyms: | Glandular kallikrein-7, submandibular/renal (rGK-7) (EC 3.4.21.35) (Esterase B) (Kallikrein-related protein K1) (Proteinase A) (RSKG-7) (Tissue kallikrein), Klk7, Klk-7 |
| UniProt Protein Function: | KLK7: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.21.35Cellular Component: apical part of cell; acrosome; nucleusMolecular Function: serine-type endopeptidase activity; endopeptidase activityBiological Process: positive regulation of acute inflammatory response; positive regulation of apoptosis; positive regulation of cell proliferation; proteolysis; response to nutrient |
| UniProt Protein Details: | |
| NCBI Summary: | serine protease; involved in processing of bioactive peptides [RGD, Feb 2006] |
| UniProt Code: | P36373 |
| NCBI GenInfo Identifier: | 6981132 |
| NCBI Gene ID: | 24523 |
| NCBI Accession: | NP_036725.1 |
| UniProt Secondary Accession: | P36373 |
| UniProt Related Accession: | P36373 |
| Molecular Weight: | |
| NCBI Full Name: | glandular kallikrein-7, submandibular/renal |
| NCBI Synonym Full Names: | kallikrein 1-related peptidase C7 |
| NCBI Official Symbol: | Klk1c7 |
| NCBI Official Synonym Symbols: | Kal; KALA; Klk1; Klk5; Klk7; Klk1l; RGK-7; RSKG-7; RATKALA |
| NCBI Protein Information: | glandular kallikrein-7, submandibular/renal; esterase B; kallikrein 5; kallikrein 7; proteinase A; renal kallikrein; tissue kallikrein; kallikrein 1-like peptidase; kallikrein-related protein K1; Kallikrein 1 renal/pancreas/salivary; Kallikrein 1, renal/pancreas/salivary |
| UniProt Protein Name: | Glandular kallikrein-7, submandibular/renal |
| UniProt Synonym Protein Names: | Esterase B; Kallikrein-related protein K1; Proteinase A; RSKG-7; Tissue kallikrein |
| Protein Family: | Kallikrein |
| UniProt Gene Name: | Klk7 |
| UniProt Entry Name: | KLK7_RAT |
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