JAM-A/CD321 Polyclonal Antibody (CAB23909)
- SKU:
- CAB23909
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
JAM-A/CD321 Polyclonal Antibody (CAB23909)
The JAM-A (CD321) Polyclonal Antibody is a valuable tool for researchers studying the cell surface molecule known as JAM-A, which is involved in various cellular processes related to immune regulation and cell adhesion. Produced by Assay Genie, this antibody is raised in rabbits and exhibits high reactivity with human samples. Validated for use in Western blot applications, this antibody specifically binds to the JAM-A protein, allowing for precise detection and analysis in a variety of cell types.JAM-A, also known as Junctional Adhesion Molecule-A, is a key player in immune response modulation and is implicated in processes such as leukocyte migration and inflammation.
Research into the function of JAM-A is essential for understanding its role in diseases such as cancer, autoimmune disorders, and inflammatory conditions. By targeting JAM-A, researchers can develop potential therapies that manipulate immune function for therapeutic benefit.The JAM-A Polyclonal Antibody from Assay Genie is an essential tool for researchers investigating the intricate mechanisms of immune regulation and cell adhesion. Its high specificity and reactivity make it an ideal choice for studies in immunology and cancer research, providing valuable insights into the role of JAM-A in health and disease.
| Product Name: | JAM-A/CD321 Polyclonal Antibody |
| Product Code: | CAB23909 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | A-431 |
Predicted to enable PDZ domain binding activity; integrin binding activity; and protein homodimerization activity. Involved in intestinal absorption; regulation of cytokine production; and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo; alimentary system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor).
| Immunogen: | Recombinant protein of human JAM-A/CD321. |
| Sequence: | Email for sequence |
| Synonyms: | JAM, Jcam, JAM-1, JAM-A, Jcam1, Ly106, ESTM33, 9130004G24 |
| Calculated MW: | 32kDa |
| Observed MW: | 36-41kDa |
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