The ITGB3 Polyclonal Antibody is a valuable tool for researchers studying integrin beta-3 (ITGB3), a cell surface receptor involved in cell adhesion and signaling. This polyclonal antibody is produced in rabbits and is highly specific for detecting ITGB3 in human samples. It has been validated for use in Western blot applications, allowing for accurate measurement of ITGB3 protein levels in various cell types.Integrin beta-3 plays a crucial role in cell adhesion, migration, and signaling processes, making it a key player in various physiological and pathological conditions.
Dysregulation of ITGB3 has been implicated in diseases such as thrombosis, cancer, and inflammatory disorders, highlighting the importance of studying its expression and function.By using the ITGB3 Polyclonal Antibody, researchers can gain valuable insights into the role of ITGB3 in cellular processes and disease pathogenesis. This antibody enables the precise detection and analysis of ITGB3 protein levels, making it an indispensable tool for research in fields such as cell biology, oncology, and cardiovascular research.
Product Name:
ITGB3 Polyclonal Antibody
SKU:
CAB24844
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-718 of human ITGB3(NP_000203.2).
Cell junction, Cell membrane, Cell projection, Single-pass type I membrane protein, focal adhesion, lamellipodium membrane.
Calculated MW:
86kDa/87kDa
Observed MW:
97kDa/130kDa
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Purification Method:
Affinity purification
Gene ID:
3690
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using ITGB3 Rabbit pAb (CAB24844) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
