| Description: | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
| Product name: | Human TMEM173 Recombinant Protein (hFc Tag) |
| Synonyms: | ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173 |
| Type: | protein |
| Size: | 50 µg |
| Name: | TMEM173 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 90% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | N-Human Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | hFc（Glu99-Ala330）+TMEM173 (Leu139-Ser379) |
| Gene ID: | 340061 |
| Uniprot: | Q86WV6 |
| Molecular Weight: | 53.2 kDa |
