Human TACO1 Recombinant Protein (RPPB4896)
- SKU:
- RPPB4896
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- TACO1
- Synonyms:
- Translational Activator Of Mitochondrially Encoded Cytochrome C Oxidase
- CCDC44
- Coiled-Coil Domain-Containing Protein 44
- Coiled-Coil Domain Containing 44
- Source:
- Escherichia Coli
- Uniprot:
- Q9BSH4
Frequently bought together:
Description
| Product Name: | Human TACO1 Recombinant Protein |
| Product Code: | RPPB4896 |
| Size: | 20µg |
| Species: | Human |
| Target: | TACO1 |
| Synonyms: | Translational Activator Of Mitochondrially Encoded Cytochrome C Oxidase, CCDC44, Coiled-Coil Domain-Containing Protein 44, Coiled-Coil Domain Containing 44, Clone HQ0477 PRO0477p, Translational Activator Of Cytochrome C Oxidase 1, Translational Activator Of Mitochondrially-Encoded Cytochrome C Oxidase I. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | TACO1 protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSNKWSKVR HIKGPKDVER SRIFSKLCLN IRLAVKEGGP NPEHNSNLAN ILEVCRSKHM PKSTIETALK MEKSKDTYLL YEGRGPGGSS LLIEALSNSS HKCQADIRHI LNKNGGVMAV GARHSFDKKG VIVVEVEDRE KKAVNLERAL EMAIEAGAEDVKETEDEEER NVFKFICDAS SLHQVRKKLD SLGLCSVSCA LEFIPNSKVQ LAEPDLEQAA HLIQALSNHE DVIHVYDNIE |
Translationalactivator of mitochondrially encoded cytochrome c oxidase I (TACO1) belongs tothe TACO1 family. TACO1 is a mitochondrial protein which functions as atranslational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutationsin this gene are associated with Leigh syndrome.
TACO1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 260 amino acids (61-297 a.a) and having a molecular mass of 28.8kDa.TACO1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CCDC44: Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1. Defects in TACO1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency. Belongs to the TACO1 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q23.3 Cellular Component: mitochondrion; nucleus Disease: Mitochondrial Complex Iv Deficiency |
| NCBI Summary: | This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010] |
| UniProt Code: | Q9BSH4 |
| NCBI GenInfo Identifier: | 33516968 |
| NCBI Gene ID: | 51204 |
| NCBI Accession: | Q9BSH4.1 |
| UniProt Secondary Accession: | Q9BSH4,Q8N3N6, Q9UI60, B2RD21, |
| UniProt Related Accession: | Q9BSH4 |
| Molecular Weight: | 32,477 Da |
| NCBI Full Name: | Translational activator of cytochrome c oxidase 1 |
| NCBI Synonym Full Names: | translational activator of cytochrome c oxidase I |
| NCBI Official Symbol: | TACO1 |
| NCBI Official Synonym Symbols: | CCDC44 |
| NCBI Protein Information: | translational activator of cytochrome c oxidase 1 |
| UniProt Protein Name: | Translational activator of cytochrome c oxidase 1 |
| UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 44; Translational activator of mitochondrially-encoded cytochrome c oxidase I |
| Protein Family: | Translational activator of cytochrome c oxidase |
| UniProt Gene Name: | TACO1 |
| UniProt Entry Name: | TACO1_HUMAN |
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