Human SIRPG Recombinant Protein (RPPB4690)
- SKU:
- RPPB4690
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- SIRPG
- Synonyms:
- Signal Regulatory Protein Gamma
- CD172 Antigen-Like Family Member B
- Signal-Regulatory Protein Beta-2
- Signal-Regulatory Protein Gamma
- Source:
- Sf9 Insect cells
- Uniprot:
- Q9P1W8
Frequently bought together:
Description
| Product Name: | Human SIRPG Recombinant Protein |
| Product Code: | RPPB4690 |
| Size: | 20µg |
| Species: | Human |
| Target: | SIRPG |
| Synonyms: | Signal Regulatory Protein Gamma, CD172 Antigen-Like Family Member B, Signal-Regulatory Protein Beta-2, Signal-Regulatory Protein Gamma, CD172g Antigen, SIRP-Gamma, SIRP-B2, SIRPB2, Signal-Regulatory Protein Beta 2, SIRP-Beta-2, SIRP Beta 2, SIRPgamma, BA77C3.1, CD172g. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | SIRPG protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPEEELQMI QPEKLLLVTV GKTATLHCTV TSLLPVGPVL WFRGVGPGRE LIYNQKEGHF PRVTTVSDLT KRNNMDFSIR ISSITPADVG TYYCVKFRKG SPENVEFKSG PGTEMALGAK PSAPVVLGPA ARTTPEHTVS FTCESHGFSP RDITLKWFKN GNELSDFQTN VDPTGQSVAY SIRSTARVVL DPWDVRSQVI CEVAHVTLQG DPLRGTANLS EAIRVPPTLE VTQQPMRVGN QVNVTCQVRK FYPQSLQLTW SENGNVCQRE TASTLTENKD GTYNWTSWFL VNISDQRDDV VLTCQVKHDG QLAVSKRLAL EVTVHQKDQS SDATPLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH |
Signal-Regulatory Protein Gamma (SIRPG) belongs to the signal-regulatory protein (SIRP) family whose members are receptor-type transmembrane glycoproteins which negatively regulate the receptor tyrosine kinase-coupled signaling processes. SIRPG is also a part of the immunoglobulin superfamily.
SIRPG Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 574 amino acids (29-360a.a.) and having a molecular mass of 64.0kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).SIRPG is expressed with a 239 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. |
| NCBI Summary: | The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9P1W8 |
| NCBI GenInfo Identifier: | 124053651 |
| NCBI Gene ID: | 55423 |
| NCBI Accession: | Q9P1W8.3 |
| UniProt Secondary Accession: | Q9P1W8,Q5D051, Q5JV25, Q5MKL4, Q8WWA5, Q9NQK8, B1AKP6 |
| UniProt Related Accession: | Q9P1W8 |
| Molecular Weight: | 29,967 Da |
| NCBI Full Name: | Signal-regulatory protein gamma |
| NCBI Synonym Full Names: | signal regulatory protein gamma |
| NCBI Official Symbol: | SIRPG |
| NCBI Official Synonym Symbols: | CD172g; SIRPB2; SIRP-B2; bA77C3.1; SIRPgamma |
| NCBI Protein Information: | signal-regulatory protein gamma |
| UniProt Protein Name: | Signal-regulatory protein gamma |
| UniProt Synonym Protein Names: | CD172 antigen-like family member B; Signal-regulatory protein beta-2; SIRP-b2; SIRP-beta-2; CD_antigen: CD172g |
| Protein Family: | Signal-regulatory protein |
| UniProt Gene Name: | SIRPG |
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