Human RAB3D Recombinant Protein (RPPB4365)
- SKU:
- RPPB4365
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- RAB3D
- Synonyms:
- Ras-related protein Rab-3D
- RAB3D
- GOV
- RAB16
- Source:
- Escherichia Coli
- Uniprot:
- O95716
Description
| Product Name: | Human RAB3D Recombinant Protein |
| Product Code: | RPPB4365 |
| Size: | 20µg |
| Species: | Human |
| Target: | RAB3D |
| Synonyms: | Ras-related protein Rab-3D, RAB3D, GOV, RAB16, D2-2, RAD3D. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | RAB3D protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.2M NaCl. |
| Stability: | RAB3D Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MASAGDTQAG PRDAADQNFD YMFKLLLIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTVYRHDKR IKLQIWDTAG QERYRTITTA YYRGAMGFLL MYDIANQESF AAVQDWATQI KTYSWDNAQV ILVGNKCDLE DERVVPAEDG RRLADDLGFE FFEASAKENI NVKQVFERLV DVICEKMNES LEPSSSSGSN GKGPAVGDAP APQPSSCSC |
Ras-related protein Rab-3D (RAB3D) belongs to the Ras superfamily of small Rab GTPases. Rab proteins play a vital role for, either in endocytosis or in biosynthetic protein transport. Rab3D mRNA is primarily expressed in white adipose tissue and, coincident with GLUT4, increases upon differentiation of 3T3-L1 fibroblasts. Rab3D exhibits close structural similarities with Rab 3A, an isoform which is functionally associated with regulated exocytosis in various cell types.
RAB3D produced in E.Coli is a single, non-glycosylated polypeptide chain containing 239 amino acids (1-219 a.a) and having a molecular mass of 26.4kDa (Molecular weight on SDS-PAGE will appear higher). RAB3D is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RAB3D: Protein transport. Probably involved in regulated exocytosis. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:G protein, monomeric; G protein, monomeric, Rab Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: cytoplasmic microtubule; plasma membrane Molecular Function:myosin V binding Biological Process: bone resorption; neutrophil degranulation |
| UniProt Code: | O95716 |
| NCBI GenInfo Identifier: | 6093901 |
| NCBI Gene ID: | 9545 |
| NCBI Accession: | O95716.1 |
| UniProt Related Accession: | O95716 |
| Molecular Weight: | 24kDa |
| NCBI Full Name: | Ras-related protein Rab-3D |
| NCBI Synonym Full Names: | RAB3D, member RAS oncogene family |
| NCBI Official Symbol: | RAB3D |
| NCBI Official Synonym Symbols: | GOV; D2-2; RAB16; RAD3D |
| NCBI Protein Information: | ras-related protein Rab-3D |
| UniProt Protein Name: | Ras-related protein Rab-3D |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB3D |
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