Human PSMG3 Recombinant Protein (RPPB4327)
- SKU:
- RPPB4327
- Product type:
- Recombinant Protein
- Size:
- 5ug
- Species:
- Human
- Target:
- PSMG3
- Synonyms:
- Proteasome assembly chaperone 3
- PAC-3
- hPAC3
- PSMG3
- Source:
- Escherichia Coli
- Uniprot:
- Q9BT73
Frequently bought together:
Description
| Product Name: | Human PSMG3 Recombinant Protein |
| Product Code: | RPPB4327 |
| Size: | 5µg |
| Species: | Human |
| Target: | PSMG3 |
| Synonyms: | Proteasome assembly chaperone 3, PAC-3, hPAC3, PSMG3, PAC3, C7orf48, MGC10911. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The PSMG3 solution (0.5 mg/ml) contains 20mM Tris-HCl Buffer (pH 8.0) and 10% Glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MEDTPLVISK QKTEVVCGVP TQVVCTAFSS HILVVVTQFG KMGTLVSLEP SSVASDVSKP VLTTKVLLGQ DEPLIHVFAK NLVAFVSQEA GNRAVLLAVA VKDKSMEGLK ALREVIRVCQ VW |
PSMG3 is a chaperone protein that promotes assembly of the 20S proteasome. PSMG3 may cooperate with PSMG1-PSMG2 heterodimers to coordinate the correct assembly of proteasomes. PSMG3 interacts with PSMG4, as well as directly with alpha and beta subunits of the 20S proteasome but dissociates prior to the formation of half-proteasomes, probably upon recruitment of POMP.
PSMG3 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 142 amino acids (1-122 a.a.) and having a molecular mass of 15.2kDa. The PSMG3 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PSMG3: Chaperone protein which promotes assembly of the 20S proteasome. May cooperate with PSMG1-PSMG2 heterodimers to orchestrate the correct assembly of proteasomes. Belongs to the PSMG3 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7p22.3 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9BT73 |
| NCBI GenInfo Identifier: | 197245458 |
| NCBI Gene ID: | 84262 |
| NCBI Accession: | NP_001127812.1 |
| UniProt Secondary Accession: | Q9BT73,A4D216, A8MPW2 |
| UniProt Related Accession: | Q9BT73 |
| Molecular Weight: | 13,104 Da |
| NCBI Full Name: | proteasome assembly chaperone 3 |
| NCBI Synonym Full Names: | proteasome (prosome, macropain) assembly chaperone 3 |
| NCBI Official Symbol: | PSMG3 |
| NCBI Official Synonym Symbols: | PAC3; C7orf48 |
| NCBI Protein Information: | proteasome assembly chaperone 3; PAC-3; hPAC3; proteasome assembling chaperone 3 |
| UniProt Protein Name: | Proteasome assembly chaperone 3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | PSMG3 |
| UniProt Entry Name: | PSMG3_HUMAN |
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